A groundbreaking method for extracting proteins from preserved soft tissues like brains has been developed, offering a unprecedented window into the past and revolutionizing our understanding of human history and prehistory.
Unlocking the Secrets of Ancient Human Brains
For the first time, we have a method for extracting proteins from preserved soft tissues like brains – which could be a treasure trove of evolutionary information. This breakthrough has significant implications for understanding human history and prehistory, as well as our evolutionary past.
Human brains contain an estimated 86 billion neurons, each capable of processing and transmitting information.
The brain's cerebral cortex is responsible for processing sensory information, controlling movement, and facilitating thought and emotion.
The hippocampus plays a crucial role in memory formation, while the amygdala processes emotions.
Brain development occurs rapidly during childhood and adolescence, with most growth taking place by age 5.
The Discovery
Brains preserved for hundreds of years can contain intact proteins. The new method developed by researchers at the University of Oxford makes it possible to obtain these proteins from soft tissues like brains. This innovation could reveal details about what animals ate, the microbes they had in their guts, and even how human brain cells changed over evolutionary time.
A New Window into the Past
Alexandra Morton-Hayward, a researcher at the University of Oxford, notes that there are soft tissues preserved over half a billion years of Earth’s history. These tissues could now be mined for proteins, providing a new window into our past. ‘The amount of information we can gain from these proteins is enormous,’ she says.
The Potential of Protein Analysis

Protein analysis has the potential to reveal a wealth of information about ancient humans and their environments. By studying the proteins preserved in brain tissue, researchers may be able to learn more about:
Protein analysis is a crucial process in understanding the structure and function of proteins.
It involves identifying, quantifying, and characterizing protein molecules using various techniques such as mass spectrometry, chromatography, and electrophoresis.
These methods help researchers determine 'protein sequences, structures, and interactions' , providing valuable insights into biological processes and diseases.
According to the National Institutes of Health (NIH), over 50% of pharmaceuticals target proteins directly or indirectly.
Protein analysis is essential in fields like biotechnology, medicine, and food science.
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What animals ate during different periods of human history
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The types of microbes that inhabited the human gut
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How human brain cells evolved over time
Human evolution began around 6-8 million years ago in Africa, with the emergence of early hominins such as Sahelanthropus tchadensis.
Over time, these species evolved into more advanced forms, including Homo habilis and Homo erectus.
The development of bipedalism, tool use, and brain expansion marked significant milestones in human evolution.
By around 300,000 years ago, Homo sapiens had begun to take shape in Africa, eventually migrating to other parts of the world.
Fossil records and genetic studies provide evidence for this gradual process.
The Significance of this Breakthrough
This breakthrough has significant implications for our understanding of human evolution and history. By analyzing proteins preserved in ancient brains, researchers may be able to gain new insights into:
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The diet and lifestyle of ancient humans
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The impact of environmental factors on human evolution
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The evolution of the human brain
- newscientist.com | We’re about to unlock the secrets of ancient human brains